Licensed pharmacological options currently available in the UK include: Orlistat : Reduces dietary fat absorption
[10] Common And Serious Side Effects Of Semaglutide Semaglutide has significant efficacy on weight loss but also has some side effects.[5,7-10] The most frequent side effects of semaglutide are gastrointestinal-related.[4,5,10,11] These include nausea, diarrhea, vomiting, constipation, upset stomach, and abdominal pain or distension.[4,5] Additional common side effects are headache, fatigue, dizziness, belching, hypoglycemia in type 2 diabetes, flatulence, gastroenteritis, gastroesophageal reflux disease, and nasopharyngitis.[5] Sometimes, more severe side effects may occur

Contact your GP or diabetes specialist nurse within 2448 hours if: The injection site reaction persists beyond one week or worsens progressively You develop signs of infection at the injection site (increasing pain, warmth, pus, or red streaking) The rash spreads beyond the injection site but without severe symptoms You experience recurrent reactions with each injection The reaction significantly impacts your quality of life or ability to continue treatment If you cannot reach your GP and need urgent advice, contact NHS 111
Avoid large protein meals within 3 to 4 hours of bedtime
Because GLP-1 medications blunt hunger cues, some women unintentionally consume too little protein or total calories, which can reduce muscle mass over time